Global Strategy Lead, PNH

About the role

Alexion, AstraZeneca Rare Disease, is looking for a Global Strategy Lead for PNH (paroxysmal nocturnal hemoglobinuria). This is a foundation role for the PNH company strategy focused on the Top 7 countries, reporting to the Global Brand Strategy Lead, Hematology. You will lead the development and profitable management of the indication with full accountability for commercialization, in a matrix model between global and local markets and across functions.

Key responsibilities

• Brand strategy: lead the VST (Value Subteam) to refine value propositions, partner with Medical and Market Access on data-generation proposals and RWE, lead the Disease Strategy Plan (DSP) and its rollout, prioritize programs, run planning meetings, lead the Competitor Response Team and report strategy and performance to senior leadership.
• Launch strategy: drive the global pre-launch plan 12-18 months before launch, give commercial input to development programs, partner with R&D, Operations, Corporate Affairs and Finance, and plan market-shaping activities with regional colleagues.
• Business and commercial performance: develop and refine positioning, messaging, buying process and patient/HCP segmentation, partner with regional commercial leads, report on global forecast development and measurement, and build stakeholder mapping.
• Pipeline: prepare business cases for assets to be assessed by the leadership team.

Required profile

• Bachelor's degree in business or life sciences.
• 10+ years in pharma or biotech, covering strategic pre-launch planning and launch, with global/regional/local experience.
• Leadership experience with a proven track record of delivering business goals in a major healthcare market.
• Profound understanding of drug development and commercialization in rare disease.
• Experience building financial business cases and knowledge of global pharmaceutical compliance and pharmacovigilance regulations.
• Preferred: advanced degree (MBA, MSc or PhD).

Required skills

• Broad marketing and commercial experience across the brand lifecycle.
• Ability to collaborate across matrix teams and influence diverse stakeholders.
• Excellent communication skills and a strong personal presence internally and externally.
• Experience integrating AI tools into cross-functional workflows.